The relationship between abdominal fat volume and obstructive sleep apnea hypopnea syndrome in obesity people / 中华整形外科杂志

<p><b>OBJECTIVE</b>To explore the relationship between abdominal fat volume and obstructive sleep apnea hypopnea syndrome in obesity people.</p><p><b>METHODS</b>From July 2009 to July 2010, 50 patients with BMI > 25 were prospectively selected for study from the patients who complained of snoring in the Respiratory department. The patients were divided into OSAHS group and non-OSAHS group according to the result of sleep apnea monitoring. All the patients also received full abdominal CT and the whole abdominal fat volume was measured by 3-D CT reconstruction system. SPSS 13.0 was used for statistical analysis.</p><p><b>RESULTS</b>The whole abdominal fat volume in the two groups was analyzed by T- test, which was significantly different between the two groups (P < 0.01). It showed that there was a statistical relationship between OSAHS and abdominal fat in obesity people.</p><p><b>CONCLUSION</b>In obesity people, OSAHS has a close relationship with abdominal fat volume. The abdominal fat volume is markedly higher in OSAHS patients than that in non-OSAHS people.</p>

Middle & distal circum peeling with bleeding control technique for redundant prepuce / 中华整形外科杂志

<p><b>OBJECTIVE</b>To investigate the middle and distal circum peeling with bleeding control technique for redundant prepuce.</p><p><b>METHODS</b>The middle and distal part of prepuce was circum peeled with bleeding control and electrical scalpel. More preputial inner plate was reserved.</p><p><b>RESULTS</b>From January 2004 to July 2008, 51 patients with redundant prepuce were treated with this procedure. The average blood loss was 1 to approximately 2 ml with minimal edema. The proportion of inner and outer plates was suitable.</p><p><b>CONCLUSIONS</b>This technique has the advantages of minimal blood loss and slight edema. The cosmetic result is also satisfactory.</p>

The long-term contrastive result of neo-urethra reconstructed with different kinds of tissue / 中华整形外科杂志

<p><b>OBJECTIVE</b>To observe the long-term apparent and structural change of the neo-urethra inner wall reconstructed with different kinds of tissue. To compare the difference between normal and reconstructed urethra for urethra reconstruction with more appropriate materials.</p><p><b>METHODS</b>The neo-urethra inner wall was observed during operation, through urography and urethroscope. The tissue section of neo-urethra inner wall was observed through light microscope and electron microscope.</p><p><b>RESULTS</b>With unchanged structure, the appearance of neo-urethra reconstructed with skin or mucosa could be close to normal urethra after a long time. Neo-urethra made of buccal mucosa possesses some of the most important basic structures for normal urethral microenvironment to form. The structure of neo-urethra made of bladder could be close to normal urethra after a long time.</p><p><b>CONCLUSIONS</b>Buccal and bladder mucosa may be a better material than skin for urethra reconstruction.</p>

Mutation analysis of SRD5A2 gene in patients with hypospadias / 中华整形外科杂志

<p><b>OBJECTIVE</b>To explore possible molecular mechanism of hypospadias and relationship of the mutation of SRD5A2 gene to hypospadias.</p><p><b>METHODS</b>96 blood samples from the patients with hypospadias were obtained and DNA was extracted from blood leukocytes. Polymerase chain reaction and direct sequencing were performed to analyze the coding regions of SRD5A2 gene.</p><p><b>RESULTS</b>8 mutations were detected from 14 cases, including 5 missense mutations, 1 synonymous mutation, 1 nonsense mutation and 1 frameshift mutation. The mutations are in 1st, 4th and 5th exon. Gln6stop, His232His, Phe234Leu and frameshift mutations are novel.</p><p><b>CONCLUSIONS</b>Exon 4 is a hot spot region of mutation within SRD5A2 gene, and about 10 percent of hypospadiac patients complicated with SRD5A2 dysfunction or deficiency.</p>

Bacteriology study of hypospadias / 中华整形外科杂志

<p><b>OBJECTIVE</b>This clinical study was to explore why the neo-urethra is liable to be infected after hypospadias operation, find the source and the common floras of infection, and accordingly, improve the peroperation procedures so as to reduce postoperative infection rate.</p><p><b>METHODS</b>The pathogenic floras were examined and analyzed by germiculture and karyotype analysis.</p><p><b>RESULTS</b>The bacteria in the neo-urethra mostly came from the orifice and the reconstruction material of the urethra. The most common floras that caused infection were gram-positive coccus. The most sensitive antibiotics for hypospadias infection were demethylvancomycin.</p><p><b>CONCLUSION</b>The postoperative infection of hypospadias is incisional, not the urinary system infection. Because the microenvironment of the neo-urethra is more suitable for infection than that of the skin or mucosa, the reconstructed urethra is likely to be infected.</p>

The inherent liability to infection of various tissue for urethra reconstruction / 中华整形外科杂志

<p><b>OBJECTIVE</b>Observing the long-term results of reconstructed urethra to reduce the postop infection rate of hypospadias. To explore the standard of selecting tissue for urethra reconstruction by comparing the different inherent liability to infection in use of different kinds of tissue for urethra reconstruction.</p><p><b>METHODS</b>Neo-urethra inner wall and normal urethra were observed through urography and urethroscope. The tissue section of neo-urethra, normal urethra and tissue for urethra reconstruction were observed through light microscope, scanning electron microscope and transmission electron microscope.</p><p><b>RESULTS</b>The structure and liability to infection of neo-urethra made of bladder mucosa, buccal mucosa or skin never changed after long time. Metaplasia never took place in neo-urethra.</p><p><b>CONCLUSIONS</b>The structure and liability to infection of neo-urethra were the same as those of the congeneric tissue. Bladder or buccal mucosa is the best tissue for urethra reconstruction considering urethra microenvironment. Neo-urethra made of skin is more liable to infection by nature. The best opportunity of hypospadias operation should be before puberty.</p>

The reverse buccinator musculomucosal flap for the treatment of inverted papilloma of the nose / 中华整形外科杂志

<p><b>OBJECTIVE</b>This paper presents the experience in using the reverse buccinator musculomucosal flap for repairing the defect following excising inverted papilloma of the nose.</p><p><b>METHODS</b>After the inverted papilloma of the nose was excised through an endonasal approach, the reverse buccinator musculomucosal flap supplied by the retrograde blood flow of the anterior buccal artery was harvested and sutured to the defect through the ora-nasal tunnel. The procedure was performed on three patients.</p><p><b>RESULTS</b>The postoperative course was uneventful. All the flaps survived completely.</p><p><b>CONCLUSIONS</b>The technique provides the solution to prevent nasal stricture from cicatricial contracture after excising inverted papilloma. In the operation, excising the inverted papilloma and repairing the defect was performed simultaneously, saving another operation for the secondary deformity. The technique is also applicable to the treatment of existing cicatricial stricture of the nose.</p>

Using scar tissue flap to repair secondary nasal deformities of unilateral cleft lip / 中华整形外科杂志

<p><b>OBJECTIVE</b>To introduce the clinical application of the upper lip scar tissue flap in correcting secondary nasal deformities of unilateral cleft lip.</p><p><b>METHODS</b>Two types of the upper lip scar tissue flap were developed in correcting nasal deformities with Millard's technique.</p><p><b>RESULTS</b>The procedure was performed on 51 patients. All the scar tissue flaps survived completely. The deformities were better corrected than before.</p><p><b>CONCLUSION</b>The scar tissue flap has adequate blood supply. This procedure is routinely combined with other commonly used techniques to correct secondary deformities of cleft lip. It is particularly applicable for repairing the nasal deformity when usable tissue is not enough.</p>

Autologous buccal mucosal graft for urethral reconstruction / 中华整形外科杂志

<p><b>OBJECTIVE</b>To search for a new method for urethra reconstruction using autologous buccal mucosal graft while lacking of local skin.</p><p><b>METHODS</b>Since 1998, a total of 25 patients with complex hypospadias have been treated using buccal mucosal grafts for urethral reconstruction. The reconstructed urethra was anastomosed with the meatus half year later.</p><p><b>RESULTS</b>All the reconstructed urethra survived without contracture or stricture except one infection, which healed with no adverse consequence.</p><p><b>CONCLUSION</b>The key points for operation success is rich capillary network, thick epidermis and thin lamina propria of the buccal mucosa. Buccal mucosa is an excellent tissue for urethral reconstruction.</p>